Ethylmalonate Market Riding Wave of Demand in Chemical Manufacturing – Forecast 2025 – 2031
The global Ethylmalonate Market was valued at US$ 47.5 million in 2024 and is anticipated to reach US$ 42.8 million by 2031, witnessing a CAGR of -1.5% during the forecast period 2025-2031.
Ethylmalonate (CAS 105-53-3) is also known as DEM, is the diethyl ester of
malonic acid. It is a colorless to pale yellow liquid with a fruity, banana,
pineapple odor. It is an important starting material in pharmaceutical and
agricultural chemical industries. It is widely used in the fields of Drug
Intermediates, dyes & pigments and flavors & fragrance.
With rising demand for pharmaceutical intermediates and
increasing R&D activity in life sciences and crop protection, the global
market for ethylmalonate is expected to see significant expansion over the next
decade.
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Market Overview
The global Ethylmalonate Market was valued at
approximately USD 65 million in 2024 and is projected to reach USD 98
million by 2031, growing at a CAGR of 6.0% from 2025 to 2031. The
growth is driven by expanding pharmaceutical production, demand for green
chemistry solutions, and the increasing need for efficient chemical
intermediates across industries.
What is Ethylmalonate?
Ethylmalonate (diethyl malonate) is a colorless,
clear liquid with a fruity odor. It is primarily used as a chemical
intermediate in the synthesis of:
- Pharmaceutical
compounds (e.g., barbiturates, vitamins like B1 and B6)
- Agrochemicals
(e.g., herbicides and pesticides)
- Flavors
and fragrances
- Dyes,
pigments, and specialty esters
Its chemical structure—featuring active methylene
groups—makes it highly reactive and suitable for a variety of organic
transformations.
Key Market Drivers
- Growth
of the Pharmaceutical Industry
Ethylmalonate is a key precursor in the synthesis of barbiturates, antihypertensive agents, and anticonvulsants. The expanding demand for generic drugs and active pharmaceutical ingredients (APIs) supports steady consumption. - Increased
Agrochemical Production
Ethylmalonate is used to manufacture herbicides and pesticides. With rising global food demand and the need to enhance crop yields, the agrochemical sector continues to drive market growth. - Demand
for Fine and Specialty Chemicals
The compound’s use in synthesizing flavors, fragrances, and dyes is rising in tandem with developments in the cosmetic and personal care industries. - Green
Chemistry and Eco-Friendly Processes
Ethylmalonate is used in environmentally friendly chemical synthesis, which aligns with global trends toward greener manufacturing practices and sustainable industrial processes.
Market Segmentation
- By
Grade:
- Industrial
Grade
- Pharmaceutical
Grade
- Food
Grade
- By
Application:
- Pharmaceuticals
- Agrochemicals
- Flavors
and Fragrances
- Dyes
and Pigments
- Others
(Polymer & Resin Synthesis, Laboratory Use)
- By
Region:
- North
America
- Europe
- Asia-Pacific
- Latin
America
- Middle
East & Africa
Regional Insights
Asia-Pacific dominates the ethylmalonate market due
to the presence of leading chemical and pharmaceutical manufacturers in China,
India, and Japan. The region benefits from low production costs,
growing exports, and rising demand in domestic markets.
North America and Europe follow closely,
driven by established pharmaceutical sectors, innovation in specialty
chemicals, and increased regulatory focus on quality and environmental
compliance.
Latin America and the Middle East & Africa
are emerging markets with growing agrochemical industries and increased
investment in healthcare infrastructure.
Key Market Players
Prominent companies in the Ethylmalonate Market include:
- Hebei
Chengxin Co., Ltd.
- Shanghai
Pu-Jie Fragrances & Flavors Co., Ltd.
- Tokyo
Chemical Industry Co., Ltd. (TCI)
- Zhejiang
Realsun Chemical Co., Ltd.
- Fushun
Shunte Chemical Co., Ltd.
- Nantong
Acetic Acid Chemical Co., Ltd.
- Merck
KGaA
- Thermo
Fisher Scientific Inc.
These players are focused on improving production
efficiency, regulatory compliance, and expanding their global reach through
partnerships and product development.
Future Outlook
- Increased
Use in Vitamin Synthesis: Ethylmalonate’s role in producing B-complex
vitamins is expected to gain traction.
- Expansion
in Custom Manufacturing: Growing demand for tailor-made chemical
intermediates in pharma and agrochemical R&D.
- Shift
Toward Sustainable Production: Emphasis on green and solvent-free
processes in chemical manufacturing will enhance adoption.
Conclusion
The Ethylmalonate Market is on a strong growth
trajectory driven by its versatility, reactivity, and growing usage in
high-value applications. With innovation in organic synthesis and increasing
demand from end-use industries, ethylmalonate will remain a critical
intermediate in the global chemical supply chain.
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